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KMID : 0367419790200020016
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Journal of Korean Pediatric Society
1979 Volume.20 No. 2 p.16 ~ p.23
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Follow-up Study of 104 Cases of Blood Exchange Transfusion for Hyperbilirubinemia
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李德雄/Lee, Deok Woong
李光燮/金興圭/金基福/Lee, Kwang Seob/Kim, Heung Kyu/Kim Ki Bok
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Abstract
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A study was made of 104 cases of neonatal hvperbilirubinemia receiving blood exchange transfusion at Kwangju Christian Hospital from January 1969 to December 1975, with the following results:
1. 5C patients(505) returned for follow-up, 9 patients(8.70) had died, and 43 patients´41. 3 o) did not return.
2. Of the 52 patients returning, developmental status was studied b%. D.D.S.T. 43 patients 1´82.7d´ had normal development, 8(15.451J) were retarded, and was questionable. No patients had a failing score. Most of the retarded patients had cerebral palsy, due to kernicterus.
3. There was no retardation among patients exchange-transfused at age of less than 5 days, or over 8 days(except 1 pts.;´, and with less than 30mgoo of :Pre-B.E.T. serum bilirubin level.
4. No significant difference of sex incidence was noted.
5. ABO incompatibility 575b; was predominant as the etiology and main cause of retarded development(19. 4%), but the idiopathic t, pe of hyperbilirubinemia;41. ? ; was interestingly high an,ong these B.E.T. patients.
6. Mean value and standard error of pre-R.E.T. serum bilirubin levels are as follows: Normal development group: 30.80=1.60
Retarded development group: 38.83-=2.35
The difference of mean values between both groups is very significant according to the t-test.
7. Motor disturbance was the predominant handicap in retarded patients at ages less than 3 years, and after this there was a tendency toward recovery, ac--ompanied by mild speech disturbance. Hearing loss, especially of high pitched tone, was noted in 1 patient and confirmed by audiomet y.
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